Bak, IstvánNguyen, Mai My Hong2021-04-272021-04-272021-04-22http://hdl.handle.net/2437/307535Hydrogen gas, which was previously considered to be physiologically inert in mammalian cells, is now considered as a novel selective antioxidant with potentially therapeutic applications and minor adverse effects. Its selectivity presents through its mild effect that is enough neither to disturb metabolic redox reactions nor to affect ROS, which function in cell signaling. This thesis reviewed the development of hydrogen in therapy, which includes its characteristic, production, possible underlying mechanisms and therapeutic applications. However, the primary targets of molecular hydrogen still remain elusive. Thus, further research is needed to determine the underlying mechanisms of therapeutic effects, antioxidant, anti-inflammatory and apoptotic ways, which will certainly advance the important molecule in clinical applications.37enmolecular HydrogenDEENK Témalista::Biológiai tudományok