Hádáné Birkó, ZsuzsannaTorner, BernadettAftab Khan, Ruqayya2024-06-042024-06-042024https://hdl.handle.net/2437/370892We aimed to compare the miRNA expression pattern in malignant tissue samples with lung adenocarcinoma-associated brain tumors and control brain tissue samples from healthy individuals, to develop a miRNA panel that can help reliably distinguish between tumor and healthy samples, potentially serving as biomarkers for adenocarcinoma-associated brain tumors. Two miRNAs, hsa-miR-200c-5p and hsa-miR-141-5p, were identified as significantly upregulated in adenocarcinoma associated brain tumor samples compared to control samples. The identification of hsa-miR-200c-5p and hsa-miR-141-5p as potential biomarkers for lung adenocarcinoma-associated brain tumors opens avenues for early diagnosis of metastatic brain tumors from lung adenocarcinoma and to distinguish it from other brain tumors.50enlung adenocarcinoma associated brain metastasismiRNAbiomarkerNGSRT-qPCRStudy of miRNAs as biomarker in lung Adenocarcinoma associated brain tumorBiology::Molecular BiologyHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.