Vasvári , GáborNguyen, Minh Huy2023-05-032023-05-032023https://hdl.handle.net/2437/351575Solid-lipid nanoparticles are tiny, spherical carriers composed of a hydrophobic core and an aqueous phase. BGP-15 is a nicotinic amidoxime derivative developed by Hungarian researchers. It is a potential antidiabetic drug candidate with cardio-, neuro-, nephro-, and photoprotective properties. During the experiment, the aim was to formulate a suitable solid-lipid micro- and nanoparticle that contains BGP-15 for controlled delivery to the site of action. Furthermore, this study was designed to evaluate the SLNs prepared by two different techniques: High shear homogenisation and Ultrasonication in terms of drug loading and entrapment efficacy, size distribution and polydispersity index.32endrug deliverynanoparticlesBGP-15BGP-15 containing Solid-lipid micro- and nanoparticles: Development and CharacterisationDEENK Témalista::Orvostudomány::GyógyszerésztudományHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.