Borbély, AttilaEhizuenlen, Joy2022-08-292022-08-292021-06-18http://hdl.handle.net/2437/336889This review aimed to summarize the currently available information on angiotensin receptor neprilysin inhibitor (sacubitril/valsartan, ARNI), a novel therapeutic approach for heart failure with reduced ejection failure (HFrEF). Drug development, pharmacokinetics, molecular and hemodynamic effects and clinical effects of ARNI were discussed38enHeart failureARNIDEENK Témalista::Orvostudomány