Borbás, AnikóKelemen, ViktorMathew, Nithin2024-04-162024-04-162024-04-08https://hdl.handle.net/2437/368839Diabetes mellitus is one of the most commonly occurring chronic, non-infectious diseases, potentially resulting in a multitude of serious, life-threatening complications if left untreated. There's been various treatments for this disease such as metformin for type 2 and subcutaneous insulin injections for type 1. Other treatments such as SGLT-2 inhibitors have been proven effective. The experiments aim to synthesize isochromane-carbohydrate derivatives that could potentially have both glycosidase inhibitory properties as well as act as SGLT-2 inhibitors using reactions oxa-Pictet-Spengler reaction and the photoinitiated thiol-ene addition reaction. Furthermore, these pharmacological and biological activities will be investigated with research collaborations.32enSGLT-2 inhibitorsType 2 Diabetes mellitusSynthetic chemistryCarbohydrate chemistryChemistry::Carbohydrate ChemistryChemistry::Organic ChemistyHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.