Lányi , ÁrpádGyöngyösi , AdriennElsaid, Fares Amgad Elmongy Abdelatti2024-06-102024-06-102024-05-02https://hdl.handle.net/2437/371308According to our research, mice models lacking Tks4 exhibited slower tumor growth when injected with LLC carcinoma and B16-F10 melanoma cells. Our study also revealed that Tks4 is present in the tumor microenvironment (TME) in both high and low TAMs, as well as Mo-MDSCs populations. Moreover, we found that Tks4-dependent maturation of BM-MDSCs requires additional signals. Overall, our study provides valuable insights into the role of Tks4 in cancer and immune system regulation.41enImmunologyMolecular biologyCell biologyCancer cellsThe effects of Tks4 adaptor protein on the tumor microenvironmentBiology::ImmunologyHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.