Juhászné Tóth, ÉvaOlta , Rushiti2026-01-082026-01-082025-11-28https://hdl.handle.net/2437/401821This thesis investigates the development of novel galectin inhibitors through the design of organometallic glycomimetics, specifically targeting the limitations of previous ruthenium-based complexes. By synthesizing new galactose-derived ligands and their corresponding platinum-group metal complexes, the study performs a detailed structure-activity relationship analysis to enhance selectivity. Ultimately, this work provides critical insights into bioorganometallic chemistry, proposing a pathway for the creation of potent, metal-based anticancer therapeutics.30enOrganic chemistryGalactin inhibitorssynthesisSynthesis of C-(galactopyranosyl)formaldehyde acylhydrazone ligands for new half-sandwich type platinum group metal complexesChemistry::Organic ChemistyBiology::BiochemistryHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.