Csávás, MagdolnaTran, Tu2021-05-032021-05-032021-03-02http://hdl.handle.net/2437/308186The continual lung infection caused by Pseudomonas aeruginosa in most cystic fibrosis cases is nowadays a major concern. Multiresistance has made the production of new antibiotics an urgent necessity. A new synthetic idea of the possible antibiotic structure in which ciprofloxacin is attached to a trivalentgalactose cluster has been generated by our understanding of the relationship between bacterial lectin PA-IL and D-galactose. The method is to use a series of cupper-mediated azide- alkyne “click” reaction to join together propargylatedtetraethyelene bridges, scaffold, sugar (D- galactose) and finally, the antibiotics itself.30enChimera AntibioticSynthesis of Galactocluster-Fluorquinolone Chimera AntibioticSynthesis of Galactocluster-Fluorquinolone Chimera AntibioticDEENK Témalista::Kémia