Pharmacological treatment of multiple sclerosis

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorSalehi, Mohammad Reza
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentBenkő, Ilona
dc.contributor.opponentSzántó, Antónia
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Belgyógyászati Intézethu_HU
dc.date.accessioned2014-06-27T13:22:11Z
dc.date.available2014-06-27T13:22:11Z
dc.date.created2014
dc.date.issued2014-06-27T13:22:11Z
dc.description.abstractBecause of autoimmunity nature of MS the main therapy is focused on immunosuppressant or immunomodulation. IFN-b and Glatimer acetate with minimal side effect profile and high efficiency to decrease relapse rate can be taken as first line treatment compared to other drugs. Mitoxantron, monoclonal antibodies, natalizumab and alemtuzumab can improve symptoms by immunosuppressory effect. Fingolimod has been shown best efficiency in aggressive form of MS as second line treatments. Vitamin D has anti-inflammatory and immunomodulatory effect which can be taken as supplementation in MS patients. Use of high dose of prednisolon or IVIG has been shown to decrease severity of symptoms and recovery significantly in relapse phase. In symptomatic management, benefit and side effects of drugs are evaluated to identify the best option of symptomatic treatment.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extentEnglishhu_HU
dc.identifier.urihttp://hdl.handle.net/2437/194933
dc.language.isoenhu_HU
dc.rights.accessno_restrictionhu_HU
dc.subjectMultiple Sclerosishu_HU
dc.subjectPharmacological treatmnthu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlePharmacological treatment of multiple sclerosishu_HU
dc.title.translatedPharmacological treatment of multiple sclerosishu_HU
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