Genetic diversity in protein-coding genes across 46 probiotic yeast isolates

A tétel rövid nézete
dc.contributor.advisorPfliegler, Valter Péter
dc.contributor.authorStanynets, Vladyslav
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biotechnológiai Intézet
dc.date.accessioned2023-04-28T08:55:54Z
dc.date.available2023-04-28T08:55:54Z
dc.date.created2023-04-27
dc.description.abstractThesis investigates the genetic diversity of various S. ‘boulardii’ strains using single nucleotide polymorphism (SNP) analysis of genomes sequenced in previous studies. In this work, 46 strains of the probiotic S. 'boulardii' were analysed with the aim to identify both common and unique SNPs and gain a better understanding of the genetic differences between these strains. Additionally, the genetic mutations of two distinct groups of isolates were examined: one from clinical sources and the other from commercial sources, to determine any significant differences and check if clinical group of samples was subjected to “in-host” selection. Through these analyses, we hope to identify any patterns or trends that suggest genetic adaptation or evolution.
dc.description.correctorLB
dc.description.courseBiochemical Engineering
dc.description.degreeBSc/BA
dc.format.extent47
dc.identifier.urihttps://hdl.handle.net/2437/351189
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectSaccharomyces cerevisiae var. 'boulardii'
dc.subjectSingle Nucleotide Polymorphisms (SNPs)
dc.subjectAdaptive mutation
dc.subjectProtein-coding genes
dc.subjectProbiotic
dc.subjectGenome analysis
dc.subject.dspaceDEENK Témalista::Biológiai tudományok::Mikrobiológia
dc.subject.dspaceDEENK Témalista::Biológiai tudományok::Genetika
dc.titleGenetic diversity in protein-coding genes across 46 probiotic yeast isolates
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Theses (Faculty of Science and Technology)