The role of the yap1 gene in the stress response of Aspergillus fumigatus

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dc.contributor.advisorIbragimova , Sandugash
dc.contributor.authorBennoui, Chahinez
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biológiai és Ökológiai Intézet
dc.date.accessioned2025-06-16T09:30:56Z
dc.date.available2025-06-16T09:30:56Z
dc.date.created2025-05-08
dc.description.abstractAspergillus fumigatus is recognized as the most common causative agent of aspergillosis, a disease whose severity depends on the host’s immune status. In immunocompromised individuals, this infection can lead to invasive aspergillosis, a life-threatening condition. A. fumigatus presents a challenge due to increasing resistance to antifungal therapies, and its ability to adapt to various stress conditions, especially those related to the immune system. The yap1 gene in A. fumigatus is known to be involved in oxidative stress response. In this study, we aimed to investigate its function under different stress conditions, including oxidative, osmotic, cell wall, and heavy metal stress. The results revealed that Yap1 is essential for oxidative stress response in A. fumigatus but does not significantly contribute to osmotic, cell wall, and heavy metal stress responses.
dc.description.courseBiology
dc.description.degreeMSc/MA
dc.format.extent38
dc.identifier.urihttps://hdl.handle.net/2437/391832
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectAspergillus fumigatus
dc.subjectInvasive aspergillosis
dc.subjectOxydative stress
dc.subjectAspergillosis
dc.subjectyap1 gene
dc.subjectFungal pathogene
dc.subject.dspaceBiology
dc.subject.dspaceBiology::Mikrobiology
dc.titleThe role of the yap1 gene in the stress response of Aspergillus fumigatus
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