The Role of the Second Alternative Oxidase Gene in Aspergillus niger

A tétel rövid nézete
dc.contributor.advisorMárton, Alexandra
dc.contributor.authorKattah, Sandra Seyram
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biotechnológiai Intézet
dc.date.accessioned2026-01-08T12:49:48Z
dc.date.available2026-01-08T12:49:48Z
dc.date.created2025-11-27
dc.description.abstractThis thesis investigates the role of the second alternative oxidase gene, aoxB, in Aspergillus niger, one of the most researched filamentous fungi for industrial citric acid production. The hypothesis states that a wild-type strain with functional aoxB and aoxA is a more productive strain than a mutant strain with a non-functional aoxB. A series of fermentation experiments, morphology experiments and growth characterization experiments in submerged and solid state revealed that aoxB presence does not significantly impact productivity under acid production settings or submerged fermentation morphology but does impact metabolic diversity in low carbon conditions. The aoxB mutant strain exhibited varying colony morphology, reduced radial growth on solid state media, and increased biomass generation at the cost of citric acid. Therefore, aoxB does not play a significant role in citric acid production but instead in continued generation and survival under stressful conditions. These results bear significance to those studying mitochondrial respiratory diversity as well as applicability to biotechnological endeavours in the field.
dc.description.courseBiochemical Engineering
dc.description.degreeBSc/BA
dc.format.extent30
dc.identifier.urihttps://hdl.handle.net/2437/401817
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectAlternative oxidase
dc.subjectAspergillus niger
dc.subjectaoxB gene
dc.subjectCitric acid production
dc.subject.dspaceBiology::Biotechnology
dc.titleThe Role of the Second Alternative Oxidase Gene in Aspergillus niger
Fájlok
Eredeti köteg (ORIGINAL bundle)
Megjelenítve 1 - 1 (Összesen 1)
Nincs kép
Név:
Thesis.SandraSeyramKattah.pdf
Méret:
1.02 MB
Formátum:
Adobe Portable Document Format
Leírás:
Megjelenítés
Engedélyek köteg
Megjelenítve 1 - 1 (Összesen 1)
Nincs kép
Név:
license.txt
Méret:
1.94 KB
Formátum:
Item-specific license agreed upon to submission
Leírás:
Letöltés
Gyűjtemények
Theses (Faculty of Science and Technology)