WGS analysis to determine mitochondrial copy numbers and their mutations in probiotic yeasts

A tétel rövid nézete
dc.contributor.advisorPfliegler, Péter
dc.contributor.authorAbdossova, Albina
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biotechnológiai Intézethu_HU
dc.date.accessioned2021-11-19T08:10:16Z
dc.date.available2021-11-19T08:10:16Z
dc.date.created2021-11-18
dc.description.abstractTo achieve significant results in the study of any organism, it is necessary to investigate the genetic material, which is decoded from the sequence of the species, in order to find out what changes in the genome can lead to certain consequences. Hence, this work aims to study certain aspects of the genome of probiotic yeast strains and clinical isolates of the same yeast, particularly mitochondrial copy numbers and their mutations and compare the commercial, mycosis, and non-mycosis isolates of S. boulardii. Throughout this thesis work, 14 isolates of S. cerevisiae yeast have been analyzed for mitochondrial DNA copy numbers and their mutations. Median coverages of mtDNA and chromosomes, petite frequency, and their correlation coefficient can be calculated to achieve the set goalhu_HU
dc.description.correctorhbk
dc.description.courseBiochemical engineeringhu_HU
dc.description.degreeBSc/BAhu_HU
dc.format.extent33hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/325063
dc.language.isoenhu_HU
dc.subjectmtDNAhu_HU
dc.subjectyeastshu_HU
dc.subjectprobioticshu_HU
dc.subject.dspaceDEENK Témalista::Biológiai tudományok::Mikrobiológiahu_HU
dc.subject.dspaceDEENK Témalista::Biológiai tudományok::Biotechnológiahu_HU
dc.titleWGS analysis to determine mitochondrial copy numbers and their mutations in probiotic yeastshu_HU
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Theses (Faculty of Science and Technology)