Inverse electron-demand Diels–Alder reactions of 3-(β-D-glucopyranosyl)-6-(het)aryl-1,2,4,5-tetrazines
Absztrakt
The ring transformation of C-glucosyl-1,2,4,5-tetrazines by means of inverse electron-demand Diels-Alder reactions with Norbonadiene and BCN conjugates was explored. These reactions afforded good yields of O-perbenzoylated 3-(beta-d-glucopyranosyl)-6-(het)aryl-pyridazines and fluorescent anellated C-(beta-d-glucopyranosyl)-6-(het)aryl-pyridazines.
Leírás
Kulcsszavak
Bioorthogonal, IEDDA, Carbohydrate, Tetrazine, Diels-Alder Reaction