Structure elucidation of a potential PET radiopharmaceutical by NMR spectroscopy

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dc.contributor.advisorTimári, István
dc.contributor.authorRossov, Aleksandr
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2025-06-18T07:15:18Z
dc.date.available2025-06-18T07:15:18Z
dc.date.created2025-05-12
dc.description.abstractIn this thesis, NMR spectra of the target molecule Ga-DOTAGA-LacN(NAP), a potential candidate for use in PET studies, were analyzed. One-dimensional ¹H spectra as well as two-dimensional TOCSY, HSQC, and HMBC spectra were examined. The spectral analysis included the determination of J-coupling constants, signal integration, and the assignment of chemical shifts for each signal. During the analysis, the structures of two saccharide residues were confirmed, signals corresponding to the DOTAGA chelate and the naphthalene fragment were identified, and chemical shifts of the aliphatic fragment were determined. The final result of the work was the assignment of each NMR signal to a specific proton or carbon atom.
dc.description.courseChemical Engineering
dc.description.degreeMSc/MA
dc.format.extent41
dc.identifier.urihttps://hdl.handle.net/2437/393164
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectGalectins
dc.subjectRadiopharmaceuticals
dc.subjectβ-D-galactopyranosyl
dc.subjectβ-D-glucopyranoside
dc.subjectMethylnaphthalene
dc.subjectMolecular structure elucidation
dc.subjectp-SCN-Bn
dc.subject.dspaceChemistry
dc.titleStructure elucidation of a potential PET radiopharmaceutical by NMR spectroscopy
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