Cellular uptake of penetratin due to the reduction of the dipole potential through statin

Abstract

Cell-penetrating peptides can be used to deliver molecular cargoes into the cell. Usually, these molecules can not cross the cell membrane, CPPs come as a method for this problem. This work focus on researching how the dipole potential from the membrane influences the CPP uptake, and how we can use statins to decrease the dipole potential and get better results for CPP concentration on the cytosol