Synthesis and structural determination of co-crystals of Furosemide

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dc.contributor.advisorAttila, Bényei
dc.contributor.authorErasga, Adlai Steven
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2024-12-17T08:40:43Z
dc.date.available2024-12-17T08:40:43Z
dc.date.created2024-11-14
dc.description.abstractChanging the structure of the unit cell of a crystal will change its properties and for co-crystals, this change is done by adding a new molecule into the unit cell. This change in structure helps produce crystals with specific properties and this has various applications like the pharmaceutical industry. Within this thesis, co-crystals are made from a loop diuretic, Furosemide, with the aims to study the structural changes and increase solubility. Furosemide is mixed with 3 co-formers: picolinic acid (pyridine-2-carboxylic acid), nicotinic acid (pyridine-3-carboxylic acid), and isonicotinic acid (pyridine-4-carboxylic acid). The produced crystals were then measured using different x-ray diffraction techniques to both prove the presence of a co-crystal as well to completely map out the unit cell of the crystal.
dc.description.courseChemical Engineering
dc.description.degreeBSc/BA
dc.format.extent24
dc.identifier.urihttps://hdl.handle.net/2437/383196
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectCrystallography
dc.subjectX-ray Diffraction
dc.subjectCo-crystals
dc.subject.dspaceChemistry::Physical Chemistry
dc.titleSynthesis and structural determination of co-crystals of Furosemide
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