Investigation of the dead cell phagocytic capacity of C2C12 myoblast cell line

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dc.contributor.advisorSarang, Zsolt
dc.contributor.authorPrakash, Sachin
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biológiai és Ökológiai Intézet
dc.date.accessioned2023-04-28T06:51:06Z
dc.date.available2023-04-28T06:51:06Z
dc.date.created2023-04-27
dc.description.abstractOur study aimed to investigate the phagocytic capacity of C2C12 mouse myoblast cells in dead cell clearance. We found that both undifferentiated and differentiated cells were capable of engulfing dead thymocytes, with undifferentiated cells being more effective. Our results demonstrate that myoblasts not only express phagocytic machinery genes but are also capable of dead cell clearance, and this process depends on TAM receptor family members, similar to professional phagocytes. These findings suggest a potential role of myoblasts in muscle regeneration and could provide insights into muscle damage and regeneration disorders.
dc.description.correctorLB
dc.description.courseBiology
dc.description.degreeMSc/MA
dc.format.extent39
dc.identifier.urihttps://hdl.handle.net/2437/351161
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectPhagocytosis
dc.subjectMyoblast
dc.subjectThymocytes
dc.subjectBiology
dc.subjectCell biology
dc.subject.dspaceDEENK Témalista::Biológiai tudományok
dc.titleInvestigation of the dead cell phagocytic capacity of C2C12 myoblast cell line
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