Fragmentation of the oligopeptides to prove their structures and identify product ions formed

A tétel rövid nézete
dc.contributor.advisorNagy, Lajos
dc.contributor.authorShi, Yiran
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2024-12-17T09:12:50Z
dc.date.available2024-12-17T09:12:50Z
dc.date.created2024
dc.description.abstractThe structure and fragmentation patterns of oligopeptides were studied in this paper, specifically tau (91-97) and tau (401-409), along with some modifications. Such modification is applied to the oligopeptides to prevent some side reactions. Tandem mass spectrometry (MS/MS) is utilized to prove the structures of these tau peptides and identify the product ions formed during the fragmentation. Although there are some limitations, since the sequence of the oligopeptides were not fully determined, the majority sequence of amino acids was, however, still successfully identified. This study aims to provide a deeper understanding of the biological role of tau peptides and its isomers, which would contribute to the prevention and treatment of neurodegenerative diseases, such as Alzheimer's disease.
dc.description.courseChemical Engineering
dc.description.degreeBSc/BA
dc.format.extent25
dc.identifier.urihttps://hdl.handle.net/2437/383199
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjecttau protein
dc.subjectoligopeptides
dc.subjectTau (91-97)
dc.subjectTau (401-409)
dc.subjectTandem mass spectrometry
dc.subjectneurodegenerative diseases
dc.subject.dspaceChemistry
dc.titleFragmentation of the oligopeptides to prove their structures and identify product ions formed
Fájlok
Eredeti köteg (ORIGINAL bundle)
Megjelenítve 1 - 1 (Összesen 1)
Nincs kép
Név:
Yiran Shi Thesis.pdf
Méret:
742.07 KB
Formátum:
Adobe Portable Document Format
Leírás:
Megjelenítés
Engedélyek köteg
Megjelenítve 1 - 1 (Összesen 1)
Nincs kép
Név:
license.txt
Méret:
1.94 KB
Formátum:
Item-specific license agreed upon to submission
Leírás:
Letöltés
Gyűjtemények
Theses (Faculty of Science and Technology)