Glycomimetics and platinum-group metal complexes as potential drugs

A tétel rövid nézete
dc.contributor.advisorJuhászné Tóth, Éva
dc.contributor.authorBaimbetova , Sholpan
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2024-12-20T09:33:27Z
dc.date.available2024-12-20T09:33:27Z
dc.date.created2024-11-28
dc.description.abstractThe thesis is a review of novel potential anticancer agents. Glycomimetics are synthetic carbohydrates, that mimics carbohydrates and play a critical role in cancer therapy by acting like inhibitirs, their structural stability and specificity make them promising alternatives to natural glycans in therapeutic applications. Platinum-group metal complexes, including platinum, ruthenium, and iridium compounds, are key components in anticancer drug development due to their ability to induce apoptosis, and overcome resistance in cancer cells. Among these, half-sandwich complexes are particularly notable for their structure, enabling engineering of their properties for enhanced selectivity, reduced toxicity, and improved activity against drug-resistant tumors. These compounds represent a significant advancement in the design of targeted, more effective anticancer treatments. Chemical Glycobiology Research Group of the Organic Chemistry Department of the University of Debrecen synthesized and patented new potential ligands for anticancer chemotherapy.
dc.description.courseBiochemical engineering
dc.description.degreeBSc/BA
dc.format.extent29
dc.identifier.urihttps://hdl.handle.net/2437/384145
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectGlycomimetics
dc.subjectPt metallodrugs
dc.subjectHalf-sandwich complexes
dc.subjectAnticancer drugs
dc.subject.dspaceChemistry
dc.titleGlycomimetics and platinum-group metal complexes as potential drugs
Fájlok
Eredeti köteg (ORIGINAL bundle)
Megjelenítve 1 - 1 (Összesen 1)
Nincs kép
Név:
Final_Thesis_Baimbetova Sholpan_ Biochem. Eng. BSc_2024.pdf
Méret:
1.19 MB
Formátum:
Adobe Portable Document Format
Leírás:
Megjelenítés
Engedélyek köteg
Megjelenítve 1 - 1 (Összesen 1)
Nincs kép
Név:
license.txt
Méret:
1.94 KB
Formátum:
Item-specific license agreed upon to submission
Leírás:
Letöltés
Gyűjtemények
Theses (Faculty of Science and Technology)