Szerző szerinti böngészés "Alabbas, Mohammad"
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Tétel Szabadon hozzáférhető Inpatient Outcomes of Cirrhosis-related Cachexia in the United States(2024) Alabbas, Mohammad; Chaar, Abdelkader; Gibson, Cheryl A.; Mohamad Alahmad, Mohamad AlhodaTétel Korlátozottan hozzáférhető Pharmacological management of heart failure with reduced EFAlabbas, Mohammad; Pórszász, Róbert; Debreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet; DE--Általános Orvostudományi Kar; Drimba, László; Szentmiklósi, József András; Debreceni Egyetem::Általános Orvostudományi Kar::Aneszteziológiai és Intenzív Terápiás Tanszék; Debreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai IntézetThis thesis aims to highlight the pharmacological agents used to treat chronic heart failure with reduced EF. Heart failure with reduced ejection fraction (HFrEF) occurrence might have risen over the previous 3 decades as a result of the emergence of numerous innovative pharmaceutical substances. Approximately 10% of sick people move forwards to much more developed phases of the disease, which are distinguished by elevated percentages of death rates, hospital admissions, as well as poor performance of living. Although being out on the best possible pharmacological, surgical, including device treatments, progressive HFrEF affected patients have persisting or developing indications of serious HF comparable to NYHA classes III or IV. Nevertheless, due to methodological limitations like decreased blood pressure as well as renal problems, a subgroup of sufferers having advanced HF, these kind of with the greatest severe forms, are been frequently underrepresented in the significant tests illustrating the effectiveness as well as reduced side effects of the medications used during HFrEF. As a result, individuals experiencing the greatest severe forms of HFrEF may not certainly benefit from the findings of many major research. Therefore, the effectiveness and tolerance of pharmacological therapy based on guidelines in individuals with the most developed forms of HFrEF frequently stay unknown, therefore this information is critical for the scheduling as well as management of recommendation considered for therapeutic strategies.Tétel Szabadon hozzáférhető [S] The Growing Epidemic of Diabetes Among the Indigenous Population of Canada: A Systematic ReviewCheran, Kaaviya; Murthy, Chinmayee; Bornemann, Elisa A; Kamma, Hari Krishna; Alabbas, Mohammad; Elashahab, Mohammad; Abid, Naushad; Manaye, Sara; Venugopal, Sathish; Alabbas, Mohammad (2024-) (xx); Belgyógyászati Intézet -- 84; ÁOK; Debreceni EgyetemDiabetes is one of the most well-known and well-researched non-communicable diseases known to humankind. The goal of this article is to show that the prevalence of diabetes is constantly increasing among indigenous people, a major population subgroup in Canada. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to conduct this systematic review, and the databases used were PubMed and Google Scholar. Studies that were published in the last 15 years (2007-2022) were selected for this review, and after applying the inclusion and exclusion criteria, screening, and removing duplicates, 10 articles were selected for the final review -three qualitative studies, three observational studies, and four studies without a specified methodology. We used the JBI (Joanna Briggs Institute) checklist, NOS (Newcastle-Ottawa Scale) checklist, and SANRA (Scale for the Assessment of Narrative Review) checklist for quality assessment. We found that all the articles showed that the prevalence of diabetes is increasing in all the Aboriginal communities despite all the interventional programs already in place. Rigorous health plans, health education, and wellness clinics for primary prevention can all be effective in reducing the potential risks of diabetes. More studies exploring the prevalence, effects, and outcomes of diabetes in the indigenous population of Canada are needed to effectively understand the disease and its complications in this group.Tétel Szabadon hozzáférhető [S] The Role of High-intensity and High-impact Exercises in Improving Bone Health in Postmenopausal Women: A Systematic ReviewManaye, Sara; Cheran, Kaaviya; Murthy, Chinmayee; Bornemann, Elisa A; Kamma, Hari Krishna; Alabbas, Mohammad; Elashahab, Mohammad; Abid, Naushad; Arcia Franchini, Ana P; Alabbas, Mohammad (2024-) (xxx); Belgyógyászati Intézet -- 84; ÁOK; Debreceni EgyetemPostmenopausal osteoporosis is a chronic condition with decreased bone mass and altered bone structure, leading to a greater risk of fractures among older women. Exercise has been proposed as a potentially effective non-pharmacological method to prevent this condition. In this systematic review, we investigate the effects and safety of high-impact and high-intensity exercises in improving bone density at popular sites of fragility fractures, namely, the hip and spine.This review also highlights the mechanism of these exercises in improving bone density and other aspects of bone health in postmenopausal women. This study is done adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. After applying the eligibility criteria, we selected 10 articles from PubMed and Google Scholar to be included in our study.Based on the findings from the studies, we established that high-intensity and high-impact exercises are effective in improving, or at the very least maintaining, bone density in the lumbar spine and femur in postmenopausal women. An exercise protocol including high-intensity resistance exercises and high-impact training is shown to be most effective in improving bone density and other parameters of bone health. These exercises were found to be safe in older women, however, careful supervision is recommended. All limitations considered, high-intensity and high-impact exercises are an effective strategy to enhance bone density, and potentially reduce the burden of fragility as well as compression fractures in postmenopausal women.Tétel Szabadon hozzáférhető [S] The Safety and Efficacy of Rituximab and Belimumab in Systemic Lupus Erythematosus: A Systematic ReviewAbid, Naushad; Manaye, Sara; Naushad, Hamzah; Cheran, Kaaviya; Murthy, Chinmayee; Bornemann, Elisa A; Kamma, Hari Krishna; Alabbas, Mohammad; Elashahab, Mohammed; Alabbas, Mohammad (2024-) (xxx); Belgyógyászati Intézet -- 84; ÁOK; Debreceni EgyetemThere is a vital role of B cells in the pathogenesis of Systemic Lupus Erythematosus (SLE). Belimumab (Bel), an inhibitor of B cell activating factor (BAFF), and Rituximab (RTX), a monoclonal antibody targeting Cd20 antigen, have been used to manage systemic lupus. Several randomized controlled trials (RCTs) have evaluated these two agents' clinical efficacy and safety in different manifestations of SLE. This study aims to review the randomized control trials involving these two agents systematically and to explain if any disparity is noticed in the primary and secondary outcomes between these two agents. This study is done according to Preferred Reporting Items for Systematic Reviews and Meta -Analyses (PRISMA) guidelines. After applying the inclusion criteria and quality assessment by independent reviewers and co-authors, relevant papers were identified, and data were extracted. The results have shown that RCTs involving Belimumab achieved primary endpoints; however, targeted endpoints were not achieved in studies involving Rituximab. It is concluded that despite the conflicting results obtained in clinical trials, both are effective in systemic lupus, as indicated in real -world clinical experience. However, better -designed multicenter studies evaluating these B -cell -targeting drugs are needed.Tétel Szabadon hozzáférhető The Efficacy of Telepsychiatry in Addiction Patients: A Systematic ReviewKamma, Hari Krishna; Alabbas, Mohammad; Elashahab, Mohammad; Abid, Naushad; Manaye, Sara; Cheran, Kaaviya; Murthy, Chinmayee; Bornemann, Elisa A; Arcia Franchini, Ana P; Alabbas, Mohammad (2024-) (xxx); Belgyógyászati Intézet -- 84; ÁOK; Debreceni EgyetemPsychiatry is one of the many medical subspecialties that have benefited from the advent of telemedicine. Substance abuse treatment via telepsychiatry expeditiously increased with the start of the pandemic and has brought changes to its rules and regulations. In this study, we focused on the prognosis of substance abuse patients treated with telepsychiatry, the various changes that occurred during the pandemic, and the difficulties faced by clinicians using telepsychiatry. PubMed and Google Scholar were searched for relevant articles between January 2010 and July 2022 using both broad and narrow keywords in addition to the MeSH (Medical Subject Heading) approach. The total number of records found was 765. Strict criteria for inclusion and exclusion ensured that only relevant information was collected. After removing duplicates, irrelevant studies, and research that did not meet the inclusion criteria, we were left with 373 studies from both electronic databases. From those, we ultimately retrieved 35 studies, which were subjected to a thorough content search and quality evaluation with the help of specialized instruments, and a total of 19 papers were included in our systematic review. We concluded that telepsychiatry use for substance abuse patients increased during the pandemic, and the prognosis of these patients treated with telepsychiatry was similar to that of in-person treatment. However, a combination of telepsychiatry with in-person sessions showed much better results.