Szerző szerinti böngészés "Alexiou, Athanasios"
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Tétel Szabadon hozzáférhető Circadian rhythm in systemic autoimmune conditions: Potential of chrono-immunology in clinical practice: A narrative review(2023) Awuah, Wireko Andrew; Huang, Helen; Kalmanovich, Jacob; Mehta, Aashna; Mikhailova, Tatiana; Cheng Ng, Jyi; Abdul-Rahman, Toufik; Adebusoye, Favour T.; Tan, Joecelyn Kirani; Kamanousa, Karl; Ferreira, Tomas; Roy, Sakshi; Kundu, Mrinmoy; Yarlagadda, Rohan; Mukerjee, Nobendu; Alexiou, Athanasios; Papadakis, MariosTétel Szabadon hozzáférhető Exploring the role of Nrf2 signaling in glioblastoma multiforme(2022) Awuah, Wireko Andrew; Abdul-Rahman, Toufik; Yarlagadda, Rohan; Mikhailova, Tatiana; Mehta, Aashna; Huang, Helen; Kundu, Mrinmoy; Lopes, Leilani; Benson, Sylvester; Mykola, Lyndin; Vladyslav, Sikora; Alexiou, Athanasios; Alghamdi, Badrah S.; Hashem, Anwar M.; Ashraf, Ghulam Md.Tétel Szabadon hozzáférhető [S] Antioxidant, anti‐inflammatory and epigenetic potential of curcumin in Alzheimer's diseaseAbdul‐Rahman, Toufik; Awuah, Wireko Andrew; Mikhailova, Tatiana; Kalmanovich, Jacob; Mehta, Aashna; Ng, Jyi Cheng; Coghlan, Megan Ariel; Zivcevska, Marija; Tedeschi, Alexander J.; de Oliveira, Emerson Costa; Kumar, Akinchita; Cantu‐Herrera, Emiliano; Lyndin, Mykola; Sikora, Kateryna; Alexiou, Athanasios; Bilgrami, Anwar L.; Al‐Ghamdi, Khalid Mohammed; Perveen, Asma; Papadakis, Marios; Ashraf, Ghulam Md; Mehta, Aashna (2025-) (xxx); DE - ÁOKAlzheimer's disease (AD) constitutes a multifactorial neurodegenerative pathology characterized by cognitive deterioration, personality alterations, and behavioral shifts. The ongoing brain impairment process poses significant challenges for therapeutic interventions due to activating multiple neurotoxic pathways. Current pharmacological interventions have shown limited efficacy and are associated with significant side effects. Approaches focusing on the early interference with disease pathways, before activation of broad neurotoxic processes, could be promising to slow down symptomatic progression of the disease. Curcumin—an integral component of traditional medicine in numerous cultures worldwide—has garnered interest as a promising AD treatment. Current research indicates that curcumin may exhibit therapeutic potential in neurodegenerative pathologies, attributed to its potent anti-inflammatory and antioxidant properties. Additionally, curcumin and its derivatives have demonstrated an ability to modulate cellular pathways via epigenetic mechanisms. This article aims to raise awareness of the neuroprotective properties of curcuminoids that could provide therapeutic benefits in AD. The paper provides a comprehensive overview of the neuroprotective efficacy of curcumin against signaling pathways that could be involved in AD and summarizes recent evidence of the biological efficiency of curcumins in vivo. © 2024 The Authors. BioFactors published by Wiley Periodicals LLC on behalf of International Union of Biochemistry and Molecular Biology.Tétel Szabadon hozzáférhető Targeting Oxidative Stress Mechanisms to Treat Alzheimer's and Parkinson's Disease: a Critical Review(2022) Aborode, Abdullahi Tunde; Pustake, Manas; Awuah, Wireko Andrew; Alwerdani, Mariam; Shah, Parth; Yarlagadda, Rohan; Ahmad, Shahzaib; Silva Correia, Inês F.; Chandra, Ayush; Nansubuga, Esther Patience; Abdul-Rahman, Toufik; Mehta, Aashna; Ali, Omar; Amaka, Shekinah Obinna; Zuñiga, Yves Miel H.; Shkodina, Anastasiia D.; Inya, Oko Christian; Shen, Bairong; Alexiou, AthanasiosTétel Szabadon hozzáférhető Tumour microenvironment: Modulating effects, challenges, and future perspectives of oncolytic virotherapy in Astrocytoma treatment(2022) Awuah, Wireko Andrew; Huang, Helen; Kalmanovich, Jacob; Mehta, Aashna; Kundu, Mrinmoy; Toufik, Abdul-Rahman; Tanna, Resham; Hasan, Mohammad Mehedi; Alexiou, Athanasios; Sikora, Vladyslav