The thesis focuses on High performance computing using software defined networking technologies. It also covers the Clos Networks and their nonblocking behavior, switch fabrics, InfiniBand, PCIe etc. The thesis consist of 4 chapters. The chapter 2 contains the theoretical background and latest research approach regarding high-speed networking. The chapter 3 solely focuses on the implementation of the Clos network Simulation, evaluation of InfiniBand and PCI express technologies. I've used software defined networking concepts. All the implementation is performed mainly in Mininet and Networl Simulator 2. The chapter 4 provides the conclusion of the thesis.