Photodynamic Therapy of Acne and Acne Scars

Abstract

This thesis reviews the clinical evidence of photodynamic therapy (PDT) for acne vulgaris and acne scars, focusing on its efficacy, mechanisms, and safety. PDT improves acne by reducing inflammation, suppressing sebum production, and eliminating Cutibacterium acnes. It also benefits acne scars by promoting tissue regeneration, reducing hyperpigmentation, and regulating collagen synthesis. However, its effectiveness for severe scars is limited and often requires combination with other treatments. The review also compares different photosensitizers and light sources to optimize therapy. Overall, PDT is a safe and effective option, though further standardization is needed for consistent clinical use.