Microsurgery and minimally invasive surgery should be considered a true reality in periodontal regenerative surgery. Several clinical trials have shown their efficacy and predictability in the treatment of intrabony defects. In 1992 microsurgery was introduced to the field of periodontics. The main fields of application in periodontology comprise root preparation, mucogingival surgery, and crown lengthening; it helps periodontal regeneration using firm techniques such as “Entire Papilla Preservation Technique”.