Antiarrhythmic drugs usage for out-of-hospital and in-of-hospital cardiac arrests: A systematic review and network meta-analysis

Abstract

we studied the effect of antiarrythmic drugs after cardiac arrest.We found no conclusive evidence that any antiarrhythmic improves rates of ROSC, survival to admission, survival to discharge or neurological outcomes. In short, no one antiarrhythmic provided throughout resuscitation has actually been shown to improve patients' outcomes. Our evaluation particularly stresses the absence of benefit of AAs in enhancing medium term results in the manner they are presently made use of. This is essential and considerable finding