Pharmacological management of Addison's disease

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorEmma-Okah, Karen
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentMegyeri, Attila
dc.contributor.opponentdeptKenézy Kórház, Aneszteziológiai és Intenziv Therápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2022-01-19T11:10:29Z
dc.date.available2022-01-19T11:10:29Z
dc.date.created2021-09-17
dc.description.abstractAddison’s disease or primary adrenal insufficiency is a rare endocrine disorder that results from the inability of the adrenal cortex to produce enough steroid hormones, cortisol and aldosterone to meet the body’s needs. Cortisol is an important hormone with diabetogenic functions. It increases appetite and blood pressure, decreases inflammatory and immune response as well as helps the body respond to stressors. It is under the regulation of the hypothalamic-pituitary-adrenal axis. ACTH stimulates the release of cortisol while cortisol inhibits its own production. Primary adrenal insufficiency presents with muscle weakness, weight loss, hypoglycaemia, depression and irritability, irregular or absent periods, impotence, hyperpigmentation etc. This lifelong disease is managed with hormone replacement therapy and regular patient follow up.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent35hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/328025
dc.language.isoenhu_HU
dc.subjectAddison'shu_HU
dc.subjectACTHhu_HU
dc.subjectAddisonian crisishu_HU
dc.subjectHyperpigmentationhu_HU
dc.subjectAdrenalhu_HU
dc.subjectInsufficiencyhu_HU
dc.subjectAdrenalitishu_HU
dc.subjectcortisolhu_HU
dc.subjectglandhu_HU
dc.subjectstresshu_HU
dc.subject.dspaceDEENK Témalista::Orvostudomány::Farmakológiahu_HU
dc.titlePharmacological management of Addison's diseasehu_HU
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