The thesis focuses on the application of cyclodextrin in enhancing the effect of Fluorouracil on HCT116 and Caco-2 cell lines. The study was designed to evaluate the potential effectiveness and interactions of these compounds in a controlled in vitro environment. The methodology used was appropriate for the research objectives and allowed for reliable and reproducible results. The findings contribute to a better understanding of how cyclodextrin can improve drug delivery. Some limitations were encountered but they did not affect the overall outcome of the study. Overall this work demonstrates the relevance of the topic and provides a foundation for further research in anticancer drug development.