Effect of a LE-127/2, a new CBG derivative, on apoptosis of melanoma cell lines
dc.contributor.advisor | Szabó , Erzsébet | |
dc.contributor.advisordept | Gyógyszerésztudományi Kar::Gyógyszerhatástani Tanszék | |
dc.contributor.author | Joby, Sneha | |
dc.contributor.department | DE--Gyógyszerésztudományi Kar | |
dc.contributor.opponent | Szabó, Zsuzsanna | |
dc.contributor.opponent | Tósaki, Ágnes | |
dc.contributor.opponentdept | Gyógyszerésztudományi Kar | |
dc.contributor.opponentdept | Klinikai Központ | |
dc.date.accessioned | 2024-04-19T09:58:38Z | |
dc.date.available | 2024-04-19T09:58:38Z | |
dc.date.created | 2024-03-03 | |
dc.description.abstract | The aim of the thesis is to find the effect of cannabinoid derivative LE-127/2 on cell proliferation and apoptosis of human melanoma cells compared to their mother CBG. According to the experimental research, it is very remarkable that LE-127/2 has less cytotoxic effect to HaCaT cells than its mother CBG. The fact that the new CBG derivative has low cytotoxicity to healthy cells could be a potential drug candidate with possibly lower side effects, so that it could be tolerated by patients in the longer term. In summary, we can also conclude that treatment with LE-127/2 leads to apoptosis, with some apoptotic proteins being activated while others do not change significantly. | |
dc.description.course | gyógyszerész | |
dc.description.courselang | angol | |
dc.description.degree | egységes, osztatlan | |
dc.format.extent | 39 | |
dc.identifier.uri | https://hdl.handle.net/2437/369057 | |
dc.language.iso | en | |
dc.rights.access | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
dc.subject | New therapeutic approach for skin cancer | |
dc.subject.dspace | Medicine::Pharmacology | |
dc.title | Effect of a LE-127/2, a new CBG derivative, on apoptosis of melanoma cell lines |
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