Rapidly Progressive Glomerulonephritis (RPGN) is a disease in the kidney which has characteristically a rapid loss of the kidney function. At least 50 percent of the kidney function is lost within a span of 3 months which is measured by the glomerular filtration rate (GFR).The main pathophysiologic feature of RPGN is the basement membrane damage and this is followed by the extra fibrin There are 3 main etiologies that lead to RPGN, which are Anti-glomerular basement membrane disease, Immune complex glomerulonephritis, Glomerulonephritis associated with vasculitis. Treatment options for RPGN are varied and in many cases, immune pathomechanisms are suspected to cause the disease and immune therapy is considered to be essential in treatment.