Modern biological treatment options for breast cancer

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorRawashdeh, Rana
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentMegyeri, Attila
dc.contributor.opponentdeptKenézy Kórház Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2021-08-18T11:44:55Z
dc.date.available2021-08-18T11:44:55Z
dc.date.created2021
dc.description.abstractBreast cancer is one of the most diagnosed cancer worldwide, it is responsible for the highest cancer related mortality rate among women in less developed countries and 2nd beside lung cancer in developed countries. Concerns regarding this fact have resulted in a well screening program as a secondary preventive measure, which was introduced parallel to the succeeding studying of the molecular level and immunological activity of breast cancer, that further allows progress in developing various treatment approaches mainly in biological treatment resulting in a noticeable decrease in recurrent rate along with increase in the survival rate of breast cancer. Taking a look among the oldest biological agent, HER2 targeting agents show significant efficacy among HER2+ overexpression tumors, which count only for a small percentage of breast cancer. However, considering other tumor characteristics like triple negative tumors, moreover, those HER2+ relapsing or resistant tumors under HER2 directed therapies, a number of new immune modulatory agents like anti PDL1 are developing nowadays and undergoing clinical trials to show promising results.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent41hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/321308
dc.language.isoenhu_HU
dc.subjectBreast Cancerhu_HU
dc.subjectBiological treatmenthu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleModern biological treatment options for breast cancerhu_HU
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Theses (Faculty of Medicine)