Pharmacological management of pulmonary hypertension

dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptdepartment of pharmacology and pharmacotherapy.hu_HU
dc.contributor.authorShammas, Adi
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentdeptKenézy Kórház Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2020-02-24T10:41:22Z
dc.date.available2020-02-24T10:41:22Z
dc.date.created2019-05-13
dc.description.abstractPulmonary hypertension is defined as an elevation in pulmonary arterial pressures (mean pulmonary artery pressure [PAP] ≥25 mmHg or an estimated systolic PAP >36 mmHg). Advances in understanding the pathobiology over the last 2 decades have led to development of both primary therapy (diuretics, digoxin, anticoagulant and oxygen supplementation) and advanced therapy (endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, and prostacyclins) initially directed at reversing the pulmonary vasoconstriction and more recently directed toward reversing endothelial cell dysfunction and smooth muscle cell proliferation.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent68hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/281200
dc.language.isoenhu_HU
dc.subjectpulmonay hypertensionhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlePharmacological management of pulmonary hypertensionhu_HU
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