The main aim of the study is to examine the effect of specific exercises and manual therapy in treating chronic low back pain amongst students, especially medical students in the second year and above. Randomly selecting students and carrying out some physical examination to determine the type and localization of pain. The indicators of this study is participants having a single primary complain of chronic low back pain, excluding other conditions like osteoporosis, metabolic bone disease, fracture, rheumatoid diseases, etc. The program involves students and physical examination, questionnaires, special test before and after intervention and finally carrying statistical evaluation within a six weeks’ period of time.