The development of entinostat in the treatment of breastcancer
| dc.contributor.advisor | Pórszász, Róbert | |
| dc.contributor.advisordept | Debreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet | hu_HU |
| dc.contributor.author | Lundström Andrianjafintrimo, Malin | |
| dc.contributor.department | DE--Általános Orvostudományi Kar | hu_HU |
| dc.contributor.opponent | Drimba, László | |
| dc.contributor.opponent | Szentmiklósi, József András | |
| dc.contributor.opponentdept | Kenézy Kórház Központi Aneszteziológiai és Intenzív Terápiás Osztály | hu_HU |
| dc.contributor.opponentdept | Debreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet | hu_HU |
| dc.date.accessioned | 2014-11-13T14:30:30Z | |
| dc.date.available | 2014-11-13T14:30:30Z | |
| dc.date.created | 2014 | |
| dc.description.abstract | The new drug entinostat is a selective histone deacetylase inhibitor with a promising future, since it seems to be a new treatment option for those patients with breast cancer, where the standard endocrine therapy is not effective. Entinostat has proven to be able to convert estrogen receptor negative tumors into estrogen receptor positive tumors and by that made the tumor succeptable to endocrine treatment. Entinostat given together with an aromatase inhibitor has shown to slow down the progression in estrogen receptor-positive breast cancer and furthermore it is very likely that entinostat can reduce the formation of new metastasis. | hu_HU |
| dc.description.course | általános orvos | hu_HU |
| dc.description.courselang | angol | hu_HU |
| dc.description.degree | egységes, osztatlan | hu_HU |
| dc.format.extent | 44 | hu_HU |
| dc.identifier.uri | http://hdl.handle.net/2437/200585 | |
| dc.language.iso | en | hu_HU |
| dc.rights | Nevezd meg! 2.5 Magyarország | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/2.5/hu/ | * |
| dc.subject | entinostat | hu_HU |
| dc.subject | breastcancer | hu_HU |
| dc.subject | treatment | hu_HU |
| dc.subject | histone deacetylase inhibitor | hu_HU |
| dc.subject.dspace | DEENK Témalista::Orvostudomány::Farmakológia | hu_HU |
| dc.title | The development of entinostat in the treatment of breastcancer | hu_HU |