pharmacological aspects of cardiac remodeling

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet
dc.contributor.authoramirideram, mahdiyeh
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentDrimba, László
dc.contributor.opponentMegyeri, Attila
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Aneszteziológiai és Intenzív Terápiás Tanszék
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet
dc.date.accessioned2022-11-16T08:57:58Z
dc.date.available2022-11-16T08:57:58Z
dc.date.created0022
dc.description.abstractThe notion of LV remodeling and its clinical implications have been progressively expanded. Cardiovascular disorders such as myocardial infarction, valvular heart disease, myocarditis, and dilated cardiomyopathy all progress in part due to cardiac remodeling. Along with cardiac myocytes, the remodeling process involves fibroblasts, extracellular matrix proteins, and the coronary vasculature. Cardiac remodeling is linked to changes in a variety of mediators, including neurohumoral hormones, cytokines, enzymes, ion channels, oxidative stress, and mechanical stress. While remodeling is primarily an adaptive reaction to maintain normal cardiac function, it becomes maladaptive with time and results in progressive decompensation. Recent research has tried to understand the molecular processes driving cardiac remodeling and to create new HF treatment methods. Modulating the remodeling process has been shown to be helpful in reversing the progression of HF.
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent36
dc.identifier.urihttps://hdl.handle.net/2437/340366
dc.language.isoen
dc.subjectcardiac remodeling
dc.subject.dspaceDEENK Témalista::Orvostudomány::Farmakológia
dc.titlepharmacological aspects of cardiac remodeling
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