Chitosan is a natural, biocompatible, biodegradable biopolymer with antimicrobial properties, making it valuable in various dental applications. It is used in prosthodontics, endodontics, periodontology, and oral surgery to promote tissue regeneration and combat infection. In endodontics, it acts as a chelating agent, improving the mechanical and antibacterial properties of dental materials. In periodontology, it supports bone healing and targeted tissue regeneration. However, chitosan has limitations such as inconsistent mechanical strength, degradation rates, and poor solubility. To overcome these challenges, researchers are exploring new chemical modifications and formulations to enhance its performance in dentistry.