Contemporary Diagnosis of Pediatric non-CML Myeloproliferative Neoplasms

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dc.contributor.advisorGáspár, Imre
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Gyermekgyógyászati Intézet
dc.contributor.authorALSMADI, NAQA
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentMahdi, Mohamed
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Infektológiai Kihelyezett Tanszék
dc.date.accessioned2023-11-23T08:43:13Z
dc.date.available2023-11-23T08:43:13Z
dc.date.created2020-07-08
dc.description.abstractIn this study, our aim was to evaluate the laboratory findings of pediatric patients with Polycythemia Vera (PV), and Essential Thrombocythemia (ET). For this, bone marrow and peripheral blood samples were collected from eight patients. Mononuclear cells were isolated and counted, then, to analyze cells, colony Forming Cell (CFC) assay was performed and colonies were counted and identified. We performed 14 CFC assays for eight cases. Colonies grew successfully for three patients and did not grow from the remaining five patients. In conclusion, analysis of cell types by CFC can aid in the confirmation of diagnosis of pediatric Ph-negative MPN even in the absence of known driver mutations.
dc.description.coursemolekuláris biológia
dc.description.courselangangol
dc.description.coursespecBiokémia-genomika
dc.description.degreeMSc/MA
dc.format.extent32
dc.identifier.urihttps://hdl.handle.net/2437/361153
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectMyeloproliferative Neoplasms
dc.subject.dspaceDEENK Témalista::Biológiai tudományok::Molekuláris biológia
dc.titleContemporary Diagnosis of Pediatric non-CML Myeloproliferative Neoplasms
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