Expression of human Transglutaminase 6 protein in prokaryotic and eukaryotic systems

dc.contributor.advisor	Király, Róbert
dc.contributor.author	Nghiem, Dan Lam
dc.contributor.department	DE--Természettudományi és Technológiai Kar--Biotechnológiai Intézet
dc.date.accessioned	2026-01-08T13:44:19Z
dc.date.available	2026-01-08T13:44:19Z
dc.date.created	2025-11-28
dc.description.abstract	Tissue transglutaminase, as known as transglutaminase 2 (TG2), is one of the most characterised members of the enzyme family. Recently, our research group recognised novel RNA-binding ability of Transglutaminase 2 (TG2). Later investigations have indicated that other transglutaminases also share this characteristic. TG6 is expressed predominantly in the central nervous system and has been implicated in neuronal development, motor coordination, and certain neurological disorders. The potential RNA-binding function of TG6 remains largely undefined. To perform its in vitro characterisation and analysis of RNA-binding capability, we developed and set up a TG6 expression system that will later enable the generation of potential site-directed TG6 mutants.
dc.description.course	Biochemical Engineering
dc.description.degree	BSc/BA
dc.format.extent	46
dc.identifier.uri	https://hdl.handle.net/2437/401826
dc.language.iso	en
dc.rights.info	Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subject	TG6
dc.subject	human transglutaminase
dc.subject.dspace	Biology::Biochemistry
dc.title	Expression of human Transglutaminase 6 protein in prokaryotic and eukaryotic systems

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