Endothelial dysfunction: pathogenesis and treatment

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dc.contributor.advisorSzentmiklósi, József András
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorZeineh, Wissam
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentPórszász, Róbert
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórház Aneszteziológiai és Intenziv Therápiás Osztályhu_HU
dc.date.accessioned2017-08-02T10:32:59Z
dc.date.available2017-08-02T10:32:59Z
dc.date.created2017-02-24
dc.description.abstractThe endothelium plays a key role in vascular homeostasis through the release of a variety of autocrine and paracrine substances. Endothelial dysfunction can be defined as the partial or complete loss of balance between vasoconstrictors and vasodilators, growth promoting and growth inhibiting factors, proatherogenic and anti-atherogenic factors. Dysfunction of endothelial cells is a systemic process and the initiating event in atherosclerosis and many other diseases, and is important in the ischemic manifestations of the disease process as well. There are different invasive and non-invsive methods to assess endothelial dysfunction. Regarding to the management of endothelial dysfunction, it is complex. Beside medications such as statins, ACE inhibitors, L-arginine, COX-2 inhibitors, lifestyle and diatery modifications should be considered, as well.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent39hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/242814
dc.language.isoenhu_HU
dc.subjectendothelial dysfunctionhu_HU
dc.subjectvascular endotheliumhu_HU
dc.subjectHaemostasis and coagulationhu_HU
dc.subjectvascular tonehu_HU
dc.subjectAtherosclerosishu_HU
dc.subjecthypertensionhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudomány::Farmakológiahu_HU
dc.titleEndothelial dysfunction: pathogenesis and treatmenthu_HU
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