Experiments for the synthesis of carbohydrate-heterocycles hybrid molecule with potential galectin inhibitor activity
| dc.contributor.advisor | Juhász, László | |
| dc.contributor.author | Bagaskara, Reyhan Kemal | |
| dc.contributor.department | DE--Természettudományi és Technológiai Kar--Kémiai Intézet | |
| dc.date.accessioned | 2026-01-08T13:49:50Z | |
| dc.date.available | 2026-01-08T13:49:50Z | |
| dc.date.created | 2025-11-25 | |
| dc.description.abstract | The aim of this research was to develop a method for synthesizing 1,2-thiodisaccharide-type galectin inhibitors with a C-galactopyranosyl-heterocyclic unit. To achieve this, a cyanogalactal was used as a key intermediate which was synthesized from D-galactose in a three-step reaction. The cyanogalactal underwent an elimination reaction to obtain the galactal derivative. The derivative was then reacted with different thiols to give the desired galactal–benzothiazole hybrid. | |
| dc.description.course | Biochemical Engineering | |
| dc.description.degree | BSc/BA | |
| dc.format.extent | 29 | |
| dc.identifier.uri | https://hdl.handle.net/2437/401828 | |
| dc.language.iso | en | |
| dc.rights.info | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
| dc.subject | Galectin inhibitor | |
| dc.subject | Carbohydrate-heterocycle hybrid | |
| dc.subject | Thiol-ene addition | |
| dc.subject.dspace | Chemistry::Organic Chemisty | |
| dc.title | Experiments for the synthesis of carbohydrate-heterocycles hybrid molecule with potential galectin inhibitor activity |
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