Exploring PD-L1 and PD-L2 as Possible Biomarkers in Renal Cancer

dc.contributor.advisorSzabó , Zsuzsanna
dc.contributor.advisordeptGyógyszerésztudományi Kar
dc.contributor.authorSEYED PIRAN, SEYED BEHRAD
dc.contributor.departmentDE--Gyógyszerésztudományi Kar
dc.contributor.opponentDobos, Nikoletta
dc.contributor.opponentSzabó, Erzsébet
dc.contributor.opponentdeptGyógyszerésztudományi Kar
dc.date.accessioned2025-04-24T07:07:22Z
dc.date.available2025-04-24T07:07:22Z
dc.date.created2025-04-23
dc.description.abstractThis study explores how two proteins, PD-L1 and PD-L2, may help predict treatment results in people with kidney cancer, specifically renal cell carcinoma (RCC). Researchers compared cancer tissue and nearby healthy kidney tissue from 20 patients and found both proteins were expressed more in tumors. Especially in aggressive tumors (Grade 4), PD-L1 and PD-L2 levels were much higher, suggesting a link between these proteins and tumor severity. One case showed unusually high PD-L1 even in a less aggressive tumor, hinting at differences between individual tumors. The findings suggest that targeting both proteins could improve treatment results, especially for high-risk patients. The study supports the use of these proteins to better match patients with the right immune therapy.
dc.description.coursegyógyszerész
dc.description.courselangangol
dc.description.degreeMSc/MA
dc.format.extent44
dc.identifier.urihttps://hdl.handle.net/2437/389342
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectRCC
dc.subjectBIOMARKER
dc.subjectPD-L1
dc.subject.dspaceBiology
dc.titleExploring PD-L1 and PD-L2 as Possible Biomarkers in Renal Cancer
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