The Effect of Oral Contraceptives on Prevention of Ovarian Cancer

Abstract

The use of oral contraceptives has long been epidemiologically known to reduce the incidence of ovarian cancer. Recently new data suggested that epigenetic changes play a vital role in the carcinogenesis of ovarian cancer. It proposes not only potential therapeutic targets and biomarkers but also a realistic opportunity for chemo prevention of ovarian cancer by combined oral contraceptives.