Recent advances in Chemotherapy of advanced stage Breast Cancer

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dc.contributor.advisorMegyeri, Attila
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorUzor, Uchechi Lois
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentPórszász, Róbert
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórház Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.date.accessioned2020-02-21T10:03:34Z
dc.date.available2020-02-21T10:03:34Z
dc.date.created2019-09-27
dc.description.abstractThe drug therapy of breast cancer includes endocrine therapy, cytotoxic chemotherapy, targeted therapy and more recently, immunotherapy. These have been developed based on tumor biological characteristics and so they are directed towards various molecular and cellular targets which are involved in tumor growth, survival and spread. The rationale behind endocrine therapy is that the drugs are able to influence the level of endogenous estrogen and also interfere with its interaction with the estrogen receptor. Targeted therapy is a widely studied class of breast cancer chemotherapy as the drugs which belong to this group are directed towards specific cellular and extracellular proteins which are involved in the pathogenesis of breast cancer. Even more recently developed are the immunotherapeutic agents which are able to induce tumor regression by enabling the immune system to recognise tumor-associated antigens as well as regulating various immunomodulatory signals.hu_HU
dc.description.correctorhbk
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent44hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/281022
dc.language.isoenhu_HU
dc.subjectdrug therapyhu_HU
dc.subjectbreast cancerhu_HU
dc.subjectchemotherapyhu_HU
dc.subjecttargeted therapyhu_HU
dc.subjectcytotoxic chemotherapyhu_HU
dc.subjectendocrine therapyhu_HU
dc.subjectimmunotherapyhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleRecent advances in Chemotherapy of advanced stage Breast Cancerhu_HU
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