Dermatological management of allergic diseases

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet
dc.contributor.authorSeyfi, Saba
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentHalasi, Barbara Dóra
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Igazságügyi Orvostani Intézet
dc.date.accessioned2023-07-20T08:15:32Z
dc.date.available2023-07-20T08:15:32Z
dc.date.created2023-02-20
dc.description.abstractAllergic skin diseases include urticarial, angioedema, contact dermatitis, and atopic dermatitis, but atopic dermatitis (AD) best represents the systemic idea of allergy. In this article, we examine the off-label and beyond-label usage of approved medications, experimental therapies in development, and interesting new targets. Recent reports of the effective use of therapies for skin allergies and prospective targets for the development of innovative treatments were looked for in MEDLINE. In addition, we searched ClinicalTrials.gov for current and recent randomized clinical studies on skin allergies. Accordingly, relevant articles were selected and reviewed. In Conclusion, innovative and superior therapies for skin allergies are urgently required. Several medicines are now in clinical trials, and other ones should be developed to exploit the numerous interesting targets recently discovered and described. Mas-related G protein-coupled receptor X2, the histamine4 receptor, C5a and its receptor, inhibitory mast cell receptors other than Siglec-8, interleukin 33, interleukin 25, thymic stromal lymphopoietin, and stem cell factor are all possible targets for future therapies.
dc.description.correctorLB
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.coursespecOrvosbiológia-farmakológia
dc.description.degreeegységes, osztatlan
dc.format.extent43
dc.identifier.urihttps://hdl.handle.net/2437/357708
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectskin Allergy
dc.subject.dspaceDEENK Témalista::Orvostudomány
dc.titleDermatological management of allergic diseases
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