third generation calcium antagonist in treatment of cardiovascular diseases

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dc.contributor.advisorSzentmiklósi, József András
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorAlmutairi, Metab
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentPórszász, Róbert
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórházy Központi Aneszteziológiai és Intenzív Terápiás Osztályhu_HU
dc.date.accessioned2018-08-02T11:24:46Z
dc.date.available2018-08-02T11:24:46Z
dc.date.created2017-03-05
dc.description.abstractCalcium channel blockers, despite former debates on side-effects and safety-problems, still hold an important position in the treatment of systemic hypertension and angina pectoris. While earlier developments have focused on increasing potency and selectivity of calcium channel blockers the most recent developments have brought about drugs which are particularly slow in onset and have a long duration of action. These drugs in this context are third generation calcium channel blockers, namely amlodipine, lercanidipine and lacidipine. These calcium channel blockers combine practically all desired effects through their high lipophilicity. They have, furthermore, an unique binding profile, which guarantees constant calcium antagonistic action independent of serum concentration changes.hu_HU
dc.description.correctorhbk
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent36hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/255922
dc.language.isoenhu_HU
dc.subjectthird generationhu_HU
dc.subjectcalcium antagonist
dc.subjecttreatment
dc.subjectcardiovascular diseases
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlethird generation calcium antagonist in treatment of cardiovascular diseaseshu_HU
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