HEMODYNAMIC COMPARISON OF EXPERIMENTAL HEART FAILURE MODELS IN THE RAT
dc.contributor.advisor | Fazekas, László | |
dc.contributor.advisordept | Általános Orvostudományi Kar::Sebészeti Műtéttani Tanszék | |
dc.contributor.author | SHAKED, OR | |
dc.contributor.department | DE--Általános Orvostudományi Kar | |
dc.contributor.opponent | Orsolya | |
dc.contributor.opponentdept | Általános Orvostudományi Kar | |
dc.date.accessioned | 2024-08-21T07:53:12Z | |
dc.date.available | 2024-08-21T07:53:12Z | |
dc.date.created | 2024-08-12 | |
dc.description.abstract | This study compares two small animal models for inducing volume-overload heart failure using arterio-venous shunts in different locations (aorto-caval and femoral) in rats. The research involved 28 female Sprague-Dawley rats, divided into three groups, with surgeries performed to create the shunts. The aorto-caval model had shorter surgery times but higher complication rates, including significant bleeding, while the femoral model showed a significant increase in blood flow post-surgery. Echocardiography revealed heart failure progression in both operated groups, with the aorto-caval group showing more severe symptoms. However, the femoral arterio-venous shunt model was deemed more favorable due to better standardization, fewer complications, and more consistent results. | |
dc.description.course | általános orvos | |
dc.description.courselang | angol | |
dc.description.coursespec | Orvosbiológia-farmakológia | |
dc.description.degree | egységes, osztatlan | |
dc.format.extent | 32 | |
dc.identifier.uri | https://hdl.handle.net/2437/379128 | |
dc.language.iso | en | |
dc.rights.access | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
dc.subject | heart failure, microsurgery, anastomosis, AV fistula | |
dc.subject.dspace | Medicine | |
dc.title | HEMODYNAMIC COMPARISON OF EXPERIMENTAL HEART FAILURE MODELS IN THE RAT |
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