Advances in pharmacology and pharmacotherapy of traumatic brain injury

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorOnazi, Ocha Ene Theresa
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórház Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.date.accessioned2019-09-26T11:58:32Z
dc.date.available2019-09-26T11:58:32Z
dc.date.created2019-04-26
dc.description.abstractThis thesis reviews various molecular targets that have an effect in Traumatic Brain Injury. It focuses on the secondary phase of injury, from acute to chronic stages, and touches on the different roles of receptors, active and passive molecules and various cells that create that environment. It highlights the various studied medications and their effects on neuro-protection, as well as neuro-support. It compares some targets and questions their combination effects, synergistic and additive. It questions what we have discovered so far, in Food and Drug Administration (FDA) approved drugs, and questions the potential of other drugs in such a category for future use in Traumatic Brain Injury. The conclusion points to the possibility of having effective combination drugs with low side effect profiles, personalized to patients with Traumatic Brain Injury to ameliorate long term sequelae.hu_HU
dc.description.correctorLB
dc.description.courseáltalános orvoshu_HU
dc.description.courselangmagyarhu_HU
dc.description.coursespecOrvosbiológia-farmakológiahu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent55hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/273786
dc.language.isoenhu_HU
dc.subjectTraumahu_HU
dc.subjectBrainhu_HU
dc.subjectNeuroprotectionhu_HU
dc.subjectPharmacologyhu_HU
dc.subjectDrugshu_HU
dc.subjectNeurosupporthu_HU
dc.subjectMolecularhu_HU
dc.subjectTargethu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleAdvances in pharmacology and pharmacotherapy of traumatic brain injuryhu_HU
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Gyűjtemények
Theses (Faculty of Medicine)