Formulation and evaluation of Philadelphus Coronarius containing topical prepration
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The growing interest in plant-based therapies has renewed focus on the use of medicinal plants like Philadelphus coronarius (mock orange) in pharmaceutical formulations. This plant, known for its antimicrobial, anti-inflammatory, and antioxidant properties, was studied for use in topical treatments for skin conditions. Extracts rich in flavonoids and tannins were obtained using ethanol and incorporated into creams, gels, and ointments. The formulations were evaluated for physicochemical properties such as pH, viscosity, spreadability, and consistency, along with stability under various environmental conditions. Microbiological and in vitro tests confirmed the antimicrobial and anti-inflammatory efficacy of the formulations. Among them, the cream formulation demonstrated the best stability, drug release, and therapeutic effectiveness. Overall, the study supports the potential of Philadelphus coronarius as a natural ingredient in dermatological products, though further clinical research is needed.