Pharmacology of new treatment of diabetes

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Megligtinides is sulphonylurea-like anti-diabetes with shorter half-life with less issues of weight gain and hypoglycemia. GLP-1 agonists and DPP4 inhibitors both act on incretin-related problems. Pramlintide, the only presentative of amylin analogue, can be used in both type 1 and 2 DM. The newest approved antidiabetes in 2013, SGLT-2 inhibitors increase the excretion of glucose in the urine which is a very unique feature. Finally, some medications of unknown mechanism on anti-hyperglycemia like colesevelam and bromocriptine become the good add-on for DM which is not in control with other anti-diabetes.

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diabetes, treatment
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