Advancements in Pharmacological Interventions for Myocardial Infarction: A Comprehensive Review of Traditional and Emerging Therapies
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The thesis "Advancements in Pharmacological Interventions for Myocardial Infarction" provides a comprehensive review of traditional and emerging therapies for myocardial infarction (MI). It examines the mechanisms, efficacy, and safety profiles of traditional drugs like thrombolytics, antiplatelet agents, and anticoagulants, which have been cornerstones in MI management. Emerging therapies, such as stem cell and gene therapy, are explored for their potential to regenerate myocardial tissue and mitigate ischemic damage. The thesis also discusses biologics targeting inflammation, oxidative stress, and apoptosis as innovative approaches for cardioprotection and tissue repair. Acute management strategies, including reperfusion therapy and symptom relief, are highlighted alongside long-term treatments like lifestyle modifications, lipid-lowering drugs, and neurohormonal blockers. The study emphasizes the importance of personalized medicine and integrating traditional and biological therapies to improve patient outcomes and advance MI management.